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br Materials and methods br Results br
2024-01-15

Materials and methods Results Discussion In the present study, we identified HBP1 as a novel substrate of AKT. This was demonstrated by in vitro phosphorylation assays and western blotting using phosphosite-specific antibodies. Three sites were identified by mass spectrometry and mutagenesi
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Corticosterone induced inhibition of OCT mediated transport
2024-01-15

Corticosterone-induced inhibition of OCT-mediated transport is rapid and appears to involve direct interaction of the steroid with the transporter at a specific site. Volk et al. (2003) studied OCT2-mediated transport by measuring substrate-induced currents using patch clamp of Xenopus oocytes exoge
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In this study high concentrations mM of thuringiensin were
2024-01-15

In this study, high concentrations (0.5–4 mM) of thuringiensin were required to stimulate the basal adenylate cyclase activity Fig. 2, Fig. 3, Fig. 4, but low concentrations of thuringiensin (1–100 μM) were sufficient to inhibit the forskolin-stimulated adenylate cyclase activity in rat cerebral cor
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Mast cells Mast cells are
2024-01-15

Mast cells. Mast RG7388 are immune cells of the myeloid lineage and are ubiquitously present in connective tissues [75]. These cells are involved in the modulation of a number of physiological functions, such as vasodilation, angiogenesis, bacterial, and parasite elimination [75]. Moreover, mast ce
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Osteoblasts have been thought to be the major cell type
2024-01-15

Osteoblasts have been thought to be the major cell type that expresses RANKL (Suda et al., 1999) which is a ligand for osteoprotegerin (OPG) and which functions as a key factor for osteoclast differentiation and activation. Recently, Nakashima and his colleagues (Nakashima et al., 2011) demonstrated
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Although CP has been an important research subject
2024-01-15

Although CP has been an important research subject in the field of antigen processing and presentation, the mechanisms of presentation of intracellular Phosphatase Inhibitor Cocktail 1 (100X in DMSO) by MHC II received considerably less attention. Interestingly, pioneering work by the Münz laborator
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br Conclusion GroEL from RA
2024-01-15

Conclusion GroEL from RA-CH-1 was expressed and purified. The recombinant RaGroEL protein exhibited ATPase activity, which cooperated with GroES in ATP hydrolysis. Furthermore, the expression pattern of groEL revealed that groEL was up-regulated during stress response. Further studies are warrant
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T7 High Yield Cy5 RNA synthesis Two parallel branches of the
2024-01-15

Two parallel branches of the DNA damage-dependent S-phase checkpoint are thought to co-operate by inhibiting distinct steps of DNA replication. One branch includes the phosphorylation of structural maintenance of chromosomes 1 (SMC1), a cohesin that is activated by ATM or ATR after IR treatment or r
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We made a number of choices in
2024-01-15

We made a number of choices in the original design of our experiments. First, we used only portions of the 5′ and 3′ regulatory elements from S. cerevisiae. The sequences of these regions were known [32] and our goal was to express the Pf-DHFR at low levels. In fact, our choice of only 600 bp of the
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br Findings br Discussion br Conclusions Midwives were more
2024-01-15

Findings Discussion Conclusions Midwives were more likely to provide effective antimalaria services (including two doses of IPT during the second and third trimesters of pregnancy) to pregnant women if Conflict of interest Authors’ contributions Funding Acknowledgements Resea
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br Removal of therapeutic doses of antibiotics from
2024-01-15

Removal of therapeutic doses of NT157 from Marek’s Disease Vaccines The impact of this change seems to vary widely among operations, probably dependent on the pre-existing quality of hatching egg production, hatchery sanitation, hatchery management, and brooding management. Increases in 7-day mo
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Our surprising results show that
2024-01-15

Our surprising results show that AAD-treated tumors adjacent to adipose tissues and in steatotic liver continue to grow in the presence of a minimal number of microvessels. In non-adipose tumor models, the similar degree of vascular suppression is translated into marked suppression of tumor growth.
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AMPK is a serine threonine
2024-01-13

AMPK is a serine/threonine protein kinase composed of a catalytic α subunit with the activating phosphorylation site (Thr172) and two regulatory subunits, β and γ. The two AMPK variants, α1 and α2, show different cellular localization in mammalian cells. AMPKα2 is detected in nuclear and non-nuclear
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Protein blast analysis of the sequence of
2024-01-13

Protein blast analysis of the sequence of globin-B with those of other ApexPrep DNA Plasmid Miniprep Column Only suggests that the globin-B domain in the HemAC-Lm displays only 6% identity and 34% similarity with that of cytoglobin/neuroglobin (Fig. 2). Furthermore, SWISS-MODEL protein modeling als
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Until now there are no report
2024-01-13

Until now, there are no report regarding the relationship of CD21 and MG. In the present study, we aimed to characterize the AchR specified Fmoc-L-Arg(Aloc)2-OH and investigated the role of CD21 in immunopathogenesis of MG. We utilized the Allophycocyanin (APC)-conjugated AchR to measure the frequen
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